PASS syndrome is a rare inflammatory disease characterized by a chronic-relapsing course of pyoderma gangrenosum, acne vulgaris, hidradenitis suppurativa and ankylosing spondylitis.
- Specific challenges associated with the recognition of the condition
Clinical features may help to make a diagnosis.
- Specific challenges associated with the diagnosis
No genetic test widely available yet. Mutations have not been detected in all cases.
- Specific challenges associated with the treatment
No drug registered. No clinical studies performed.
- Specific challenges associated with care of these patients over their lifespan – Quality of life issues – Gaps accross the care
Skin scarring due to severe acne, pyoderma gangraenosum and hidradenitis suppurativa / acne inversa is prominent.
Incidence : unknown
Prevalence : unknown